PhD Position at the Department of Biology (f/m/d)

(fulltime)

Generic DRUGtrain project description and mandatory MSCA-mobility rule Salary Scale according to Marie Curie International Training Network definitions.

Reference Number 2021/121.The foreseen starting date is October 2021. The anticipated duration of the project will be three years.

The University of Konstanz is one of eleven Universities of Excellence in Germany. Since 2007 it has been successful in the German Excellence Initiative and its follow-up programme, the Excellence Strategy.

DRUGtrain is an EU MSCA-funded Research Training Network offering a timely paradigm for multidisciplinary research on the improvement of drug repurposing and development of compound strategies, with Autosomal Dominant Polycystic Kidney Disease (ADPKD) as example.

DRUGtrain offers innovative, multidisciplinary and intersectoral training to 9 Early Stage Researchers introducing them in the field of drug repurposing and discovery to enhance career perspective in an expanding area that underpins innovative technological development across a range of diverse disciplines.

The group of Human and Environmental Toxicology under the leadership of Prof. Daniel Dietrich will investigate the off-target toxicity of repurposed ADPKD drugs in human and mouse renal epithelial cell systems/organoids using in vitro transwell systems for in vitro to in vivo extrapolations as a basis for human risk benefit calculations.
Six universities, four private sector companies and 1 NGO will join forces to train a next generation of multidisciplinary researchers in biomedical and (bio)pharmaceutical sciences.

Specific requirement for this MSCA-funded position: At the time of selection, the candidate must not have resided or carried out the main activity (work, studies, etc.) in the country of the host organisation (Germany) for more than 12 months in the 3 years immediately prior to the recruitment.

Your responsibilities

Characterization of drug induced nephrotoxicity in vitro using static and micro-fluidic systems with human and murine renal proximal tubule cells and glomerular cells. In vitro to in vivo extrapolations for better human risk benefit calculations

Your Competencies

We are seeking a motivated PhD student with a Master in Biology or Life Science. Experience in molecular biology, biochemistry and cell culture techniques is prerequisite

We Offer

A timely paradigm for multidisciplinary research on the improvement of drug repurposing and development of compound strategies, with Autosomal Dominant Polycystic Kidney Disease (ADPKD) as example

Questions can be directed to the Secretary of the Chair of Human and Environmental Toxicology via E-mail: pia.zettler@uni-konstanz.de.

We look forward to receiving your application (include your CV, your Masters Degree/a transcript of current study status, a motivation letter and two letters of reference or reference contacts) until June 30, 2021 via our Online Application Portal.

The University of Konstanz is committed to ensuring an environment that provides equal opportunities and promotes diversity as well as a good balance between university and family life. As an equal opportunity employer, we strive to increase the number of women working in research and teaching. We also support working couples through our dual career programme (https://www.uni-konstanz.de/en/equalopportunities/family/dual-career/). Persons with disabilities are explicitly encouraged to apply. They will be given preference if appropriately qualified (contact + 49 7531 88–4016).

 

 

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